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[Chemical Knowledge]：Proper Use and Precautions of Thionyl Chloride

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Thionyl chloride (Thionyl chloride) is a commonly used acid chloride reagent, which is widely used in organic synthesis, pharmaceutical manufacturing and other fields. The correct use of thionyl chloride as acid chloride is essential, otherwise it may cause accidents or waste chemicals. Below we will introduce in detail the matters needing attention of thionyl chloride. Wear protective goggles, gloves, and lab clothes when using thionyl chloride as an acid chloride

. Thionyl chloride is irritating to the skin and eyes. After contact, rinse with plenty of water immediately and seek medical attention immediately.

operation should be carried out in a well-ventilated laboratory to avoid harm to human body caused by thionyl chloride vapor. Use an explosion-proof exhaust hood or heat and stir to add thionyl chloride to reduce volatilization.

need special attention is that the reaction of thionyl chloride and water can produce a violent chemical reaction, resulting in toxic hydrogen chloride gas, so do not let thionyl chloride contact water or moisture.

In addition, thionyl chloride can react with many organics to generate heat and may even cause a fire. When mixed with other chemicals, the experimental procedures should be strictly followed to avoid the production of hazardous substances. After the

is used, the residual thionyl chloride should be sealed and stored. Thionyl chloride is extremely sensitive to air and moisture and should be kept away from humid and high temperature environments to prevent volatilization and leakage.

Proper use of thionyl chloride as an acid chloride is critical to laboratory personnel and laboratory safety. I hope everyone can strictly abide by the operating procedures when using thionyl chloride, do a good job of protection, ensure the smooth progress of the experiment, and ensure the safety of personal safety and laboratory environment.

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