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[Chemical Knowledge]：Properties and Uses of Ethyl Propyl Cyanoacetate

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Ethyl propyl cyanoacetate is an important organic chemical raw material, which is widely used in medicine, pesticide, dye and other fields. In this paper, the properties, uses and production processes of ethyl propyl cyanoacetate are introduced in detail.

1. the properties of ethyl propyl cyanoacetate

ethyl propyl cyanoacetate is a colorless and transparent liquid with a pungent odor. Its molecular formula is C8H13NO2, the structure contains cyano, ester and other functional groups, so that it has good reactivity. The melting point of ethyl propylcyanoacetate is -48°C, the boiling point is 220-222°C, and the density is 1.01g/cm3. It is insoluble in water, soluble in organic solvents, such as ethanol, ether and so on.

2. propyl cyanoacetate uses

1. pharmaceutical intermediates: propyl cyanoacetate is an important pharmaceutical intermediates, can be used for the synthesis of antibacterial drugs, anticancer drugs, antiviral drugs and other drugs. For example, it can be used as an intermediate for the synthesis of the antibiotic drug amoxicillin.
2. pesticides: propyl cyanoethyl acetate can be used for the preparation of pesticides, fungicides and other pesticides. It has good biological activity and good control effect on crop diseases and insect pests.
3. Dyes: ethyl propyl cyanoacetate can be used as a dye intermediate for the synthesis of dyes of various colors. For example, it can be used to synthesize red dyes.

3. of ethyl propyl cyanoacetate production process

of ethyl propyl cyanoacetate production methods mainly include esterification, cyanidation and so on. The following is a brief introduction of esterification production process:

1. raw material preparation: the propanol, cyanoacetic acid, catalyst and other raw materials according to a certain proportion of ready.
2. esterification reaction: under the action of catalyst, the esterification reaction of propanol and cyanoacetic acid is carried out to generate ethyl propyl cyanoacetate.
3. Distillation purification: by distillation, the reaction of ethyl propyl cyanoacetate and unreacted raw materials are separated to obtain high purity ethyl propyl cyanoacetate products.

4. precautions

In the process of producing and using ethyl propyl cyanoacetate, the following matters need to be paid attention to:

1. Safety protection: ethyl propyl cyanoacetate has certain toxicity, and contact with skin and inhalation of its vapor should be avoided. Personal protective equipment such as protective gloves, glasses and respirators should be worn during operation.
2. storage and transportation: propyl cyanoacetate should be stored in a cool, ventilated warehouse, away from fire and heat sources. During transportation, collision and dumping shall be prevented, and direct sunlight and high temperature environment shall be avoided.
3. Waste disposal: waste propyl cyanoacetate should be safely disposed in accordance with relevant laws and regulations to avoid harm to the environment and human body.

In short, as an important chemical raw material, propyl cyanoacetate has a wide range of applications in medicine, pesticides, dyes and other fields. In the process of production and use, the relevant safety operation procedures should be strictly observed to ensure product quality and production safety.

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