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[Chemical Knowledge]：Properties and Uses of Acetophenone

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Acetophenone is an important organic chemical raw material, which is widely used in the fields of medicine, pesticide, spice and plastic. This article will detail the properties and uses of acetophenone.

1. the properties of acetophenone

acetophenone is a colorless or yellowish transparent liquid with a pleasant aroma. It is insoluble in water, but soluble in alcohol, ether, acetone and other organic solvents. The chemical properties of acetophenone are more active, prone to addition, oxidation, reduction and other reactions.

1. addition reaction

the carbonyl carbon atom of acetophenone has certain electrophilicity and can react with nucleophiles. For example, reaction with a Grignard reagent can produce phenethyl alcohol.

2. oxidation reaction

acetophenone can be oxidized by oxidizing agent to produce benzoic acid. Commonly used oxidants include potassium permanganate, chromic acid, etc.

3. reduction reaction

acetophenone can be reduced by reducing agent to generate phenylacetaldehyde. Commonly used reducing agents include lithium aluminum hydride, sodium borohydride, and the like.

2. the use of acetophenone

acetophenone as an important organic chemical raw material, widely used in medicine, pesticides, spices and plastics and other fields. The application of acetophenone in various fields will be described in detail below.

1.

in the field of medicine Acetophenone can be used as an intermediate in the synthesis of drugs for the preparation of anti-inflammatory, anti-cancer, antibacterial and other drugs. For example, acetophenone can be reacted with aniline to form phenylacetamide, a commonly used pharmaceutical intermediate that can be used to prepare anti-tuberculosis drugs.

2.

in the field of pesticides Acetophenone can be used as an intermediate in the synthesis of pesticides for the preparation of pesticides, fungicides, herbicides and other pesticides. For example, acetophenone can be reacted with chloropicrin to form acetophenone oxime, a commonly used fungicide that can be used to control diseases such as rice sheath blight.

3. spice field

acetophenone has a pleasant aroma, can be used as spices for food additives, daily chemical products. For example, acetophenone can be used as a flavor to formulate flavors for foods such as candy and beverages.

4.

in the field of plastics Acetophenone can be used as a plastic additive to improve the toughness, impact strength and other properties of plastics. For example, acetophenone can be used as a plasticizer in plastics such as polyvinyl chloride to improve their processability and mechanical properties.

In conclusion, as an important organic chemical raw material, acetophenone has a wide range of applications in the fields of medicine, pesticides, spices and plastics.

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