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[Chemical Knowledge]：Properties and Uses of o-Methyl Anisole

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The properties and uses
of o-methyl anisole
o-methyl anisole (O-Methylanisole) is a common chemical raw material, with unique properties and a wide range of uses. In this paper, the properties, synthesis methods, application fields and safety measures of o-methyl anisole are introduced in detail in order to deepen the understanding and understanding of it.

1. the properties of o-methyl anisole

o-methyl anisole is a colorless and transparent liquid with a special smell. Its molecular formula is C8H10O and its molecular weight is 122.17. The boiling point of o-methyl anisole is 194~196 ℃, the melting point is -36.5 ℃, the relative density is 0.9936(20/4 ℃), the refractive index is 1.5127, and the flash point is 71 ℃. In addition, o-methyl anisole is insoluble in water, but is miscible with organic solvents such as alcohols and ethers. The synthesis method of

2. o-methyl anisole

o-methyl anisole can be synthesized by various methods, including:

1. Alkylation of anisole with methanol in the presence of acidic catalyst;
2. Etherification of phenol with methanol under acidic conditions to produce o-methyl phenol, and then reaction with dimethyl sulfate to produce o-methyl anisole;
3. Reaction of phenol with dimethyl sulfate to produce o-methyl phenol sulfate, and then with methanol transesterification reaction to generate o-methyl anisole.

3. o-methyl anisole

o-methyl anisole as an important chemical raw material, is widely used in the following fields:

1. pharmaceutical intermediates: o-methyl anisole can be used as pharmaceutical intermediates for the synthesis of antibacterial drugs, anti-inflammatory drugs, anti-cancer drugs and other drugs.
2. Perfume manufacturing: o-methyl anisole has a special smell and can be used in perfume manufacturing to provide aroma components for food, cosmetics and other industries.
3. Solvent: o-methyl anisole can be used as a solvent for the production of coatings, inks, resins and other products.

4. safety measures

need to take the following safety measures when operating o-methyl anisole:

1. Avoid contact with open flames, high heat and other substances that are easy to cause combustion;
2. Wear protective clothing, gloves and other personal protective equipment to avoid direct contact with o-methyl anisole;
3. Operate in a well-ventilated environment to avoid inhaling the vapor of o-methyl anisole;
4. Store in a cool, dry, well-ventilated warehouse, away from fire, heat and other dangerous factors.

In conclusion, o-methyl anisole, as a common raw material for the production of chemical products, has unique properties and a wide range of uses. In the process of use, it is necessary to strictly abide by the safety operation procedures to ensure production safety.

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