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[Chemical Knowledge]:What about mannitol crystallization

Mannitol is an organic compound with wide application value, which is commonly used in the manufacture of cosmetics, drugs and food. However, during the processing of mannitol, it is easy to form crystals because of its solubility. The problem of mannitol crystallization not only affects the product quality, but also affects the production efficiency and economic benefits. Then, what about mannitol crystallization? Next, this article will introduce the causes and solutions of mannitol crystallization in detail. The reason

1. the crystallization of mannitol

mannitol in the process of processing, because its solubility in water is not high, easy to form crystals. Especially in winter, the crystallization at low temperature will be more obvious. At the same time, the crystallization of mannitol may also be caused by factors such as chemical reactions or errors in control parameters. Mannitol crystallization will not only affect the performance of the product, but also cause some trouble to the production. Therefore, some measures need to be taken to solve this problem.

2. Mannitol Crystallization Solution

1. Heating Solution

Mannitol Crystallization The simplest method is to re-dissolve it by heating. This solution can use a water bath or direct heating. It can quickly dissolve crystals and return to the liquid state. However, too high temperature will damage the quality of mannitol, so it is necessary to control the temperature during heating to avoid too high temperature.

2. Recrystallization treatment

Recrystallization treatment refers to the re-dissolution of crystalline mannitol, and then through the crystallization process, so that the crystalline mannitol particle size is more fine, and even can reach the micron level, improve the quality and performance of the product. In addition, the recrystallization treatment also has certain economic benefits, can use the crystallization of mannitol for recycling, reduce waste and energy waste.

3. Addition of an anti-crystallizing agent

Mannitol crystallization can be prevented by addition of an anti-crystallizing agent. Anti-crystallizing agents can slow down the crystallization of mannitol, making it less likely to form crystals. The choice of anti-crystallization agent needs to be adjusted according to the actual situation. At present, the commonly used anti-crystallization agents in the market include polyvinylpyrrolidone, polyethylene oxide, etc.

4. adjusting control parameters

mannitol crystallization problems may also be due to control parameters or chemical reactions and other reasons. In the processing process, it is necessary to strengthen the quality control, and continuously adjust the control parameters according to the characteristics of the production process to keep the mannitol in a stable state.

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