[Chemical Knowledge]：The nature, use, upstream and downstream raw materials, storage methods, o-chloroaniline price.

Properties of o-Chloroaniline

o-Chloroaniline (o-Chloroaniline,CAS number: 95-51-2) is an aromatic amine with the molecular formula C6H6ClN and a molecular weight of 127.57g/mol. Its pure substance is a colorless to pale yellow liquid with a faint ammonia odor. o-Chloroaniline has a melting point of -2°C, a boiling point of 209°C, and a density of 1.213g/cm³. It is miscible with many organic solvents, but has a low solubility in water. In terms of chemical properties, the amino group (-NH2) and chlorine atom (-Cl) of o-chloroaniline make it show certain activity in chemical reactions, especially its amino group can react with a variety of compounds to generate a variety of organic intermediates.

Application of o-chloroaniline

O-chloroaniline is mainly used as an intermediate in organic synthesis, and is widely used in the fields of dyes, pharmaceuticals and pesticides. In the dye industry, o-chloroaniline is an important raw material for the synthesis of acid dyes and direct dyes, such as the production of dye intermediates o-chloroaniline -4-sulfonic acid (CAS number: 95-82-9). In medicine, o-chloroaniline can be used in the manufacture of antibacterial drugs, anticancer drugs. For example, it is a synthetic precursor of the anticancer drug cyclophosphamide. In the field of pesticides, o-chloroaniline can be used in the synthesis of herbicides and insecticides, such as the common herbicide chloraniline.

Upstream raw material

The production of o-chloroaniline mainly takes benzene as the starting material, which is realized by two-step reaction of chlorination and amination. Benzene is chlorinated to generate chlorobenzene (CAS number: 108-90-7); then, chlorobenzene is ammoniated with ammonia under the action of a catalyst to generate o-chloroaniline. The chlorination reaction is generally carried out under the action of iron powder or ferric chloride catalyst, while the ammoniation reaction mostly uses metal catalysts such as copper or molybdenum. The control of reaction temperature and pressure is essential to improve the yield and selectivity.

o-Chloroaniline Downstream Products

As an intermediate, o-chloroaniline can be further processed into a variety of chemical products. In the dye industry, it can be nitrated to produce 2-chloro-4-nitroaniline, which in turn is used to produce acid and direct dyes. In pharmaceutical synthesis, it can be converted to a variety of pharmaceutical intermediates, such as cyclophosphamide. o-chloroaniline is also used in the production of some special chemicals, such as some components in photosensitive materials.

STORAGE METHOD OF O-CHLOROANILINE

Due to the toxicity and corrosiveness of o-chloroaniline, its storage requires special attention. Under normal circumstances, o-chloroaniline should be stored in a sealed corrosion-resistant container, in a cool, dry, well-ventilated warehouse, away from fire and heat sources. The storage environment temperature should not be too high to prevent excessive internal pressure in the container or liquid evaporation. Wear appropriate personal protective equipment such as protective gloves, goggles and protective clothing to avoid direct contact. In case of leakage, it should be cleaned up in time and treated with appropriate adsorption materials to prevent diffusion.

Safety and Environmental Considerations

O-chloroaniline has certain pollution risks to the environment, especially to water and soil. Therefore, management should be strengthened during production and use to prevent leakage and discharge. Waste water, waste gas and solid waste shall be discharged after being treated to meet the standards. Workplaces should be equipped with appropriate ventilation and emergency eyewash equipment to deal with accidental contact and leakage. Training operators to improve their safety awareness and emergency response capabilities is also an important measure to ensure safe production.

Market Prospects and Challenges

o-Chloroaniline is widely used in many industrial fields, and the market demand is stable. With the increasingly stringent environmental regulations, pollution control in the production and use of o-chloroaniline has become one of the main challenges facing enterprises. To meet this challenge, companies need to invest in environmental protection facilities and technologies to reduce "three wastes" emissions. Developing green processes and finding more environmentally friendly alternatives are also the future direction of development. Changes in demand in the international market and fluctuations in raw material prices also have an impact on the development of the o-chloroaniline industry. Through technological innovation and management improvement, companies can remain competitive in a highly competitive market.

Conclusion

As an important chemical intermediate, o-chloroaniline plays an important role in the fields of dyes, pharmaceuticals and pesticides. Its production involves complex chemical reactions and has strict requirements on raw materials and reaction conditions. Pay attention to safety protection and environmental protection during storage and use. Facing the dual challenges of market and environmental protection, the industry needs to achieve sustainable development through technological innovation and strict management. With the development of related fields, the market prospect of o-chloroaniline is still broad, but it is necessary to constantly meet the challenges and maintain technological leadership and environmental compliance.