[Chemical Knowledge]：Properties, uses, upstream and downstream raw materials, storage methods, synthesis of chloroisobutane

Properties of chloroisobutyl ketone

Chloroisobutyl ketone (Chloroacetone) is an organic compound with the chemical formula C4H7ClO. This compound appears as a colorless to light yellow liquid at room temperature, with a strong pungent and corrosive odor. Its boiling point is between 120-121°C and its density is about 1.1g/cm³. Chloroisobutyl ketone is easily soluble in ethanol, ether and other organic solvents, but the solubility in water is poor. Due to its active chloro group and carbonyl group, chloroisobutyl ketone can react with a variety of chemical reagents and has certain chemical reactivity.

Chloroisobutyl ketone use

Chloroisobutyl ketone is widely used in the chemical industry, mainly including the following aspects:

1. Chemical synthesis intermediates

As an important intermediate in organic synthesis, chloroisobutyl ketone is widely used in the synthesis of pharmaceuticals, pesticides, dyes and fragrances. For example, in the pharmaceutical industry, it can be used to synthesize key parts in certain drug molecules. In the production of pesticides, chloroisobutyl ketone can be used as a pesticide intermediate, which can be further reacted to produce compounds with insecticidal or herbicidal effects.

2. Coatings and resins

In the coatings and resins industry, chloroisobutanone is used to synthesize some special resins and curing agents. These resins and curing agents have excellent chemical resistance and mechanical properties, which can improve the durability and corrosion resistance of the coating.

3. Chemical Reagents

Chloroisobutyl ketone is also used as a chemical reagent in the laboratory, especially in organic synthesis research. Because of its unique chemical properties, researchers can use it to carry out a series of organic chemical reactions and explore new reaction pathways and synthetic methods.

Chlorinated isobutyl ketone upstream and downstream raw materials

Upstream raw materials

The production of chloroisobutyl ketone mainly involves several key upstream raw materials:

1. Isobutyl ketone (Methyl isobutyl ketone, MIBK): Isobutyl ketone is the basic raw material for the production of chloroisobutyl ketone, which can be obtained by chlorination reaction.

2. Chlorine (Chlorine): Chlorine is used for chlorination in the synthesis of chloroisobutyl ketone, so chlorine is also one of its important upstream raw materials.

3. Catalyst: In the reaction process, the appropriate catalyst can promote the chlorination reaction and improve the yield and purity of the product.

Downstream Products

Chloroisobutyl ketone is used as an intermediate in the production of a range of downstream products:

1. Pharmaceutical intermediates: used for the synthesis of antibacterial drugs, antiviral drugs and other pharmaceutical products.

2. Pesticide intermediates: used in the synthesis of pesticides, herbicides and other pesticide products.

3. Dyes and pigment intermediates are used to produce certain high-performance dyes and pigments to improve their dyeing effect and stability.

Chloroisobutyl ketone storage method

Storage conditions

Due to the chemical nature of chloroisobutyl ketone is relatively active and corrosive, the following points need to be paid special attention to during storage:

1. Protect from light and moisture: Chloroisobutanone should be stored in a cool, dry, well-ventilated warehouse, away from direct sunlight and moisture to prevent its decomposition and deterioration.

2. Sealed containers: Chloroisobutyl ketone should be stored in a well-sealed container to prevent its volatilization and leakage. Glass or corrosion-resistant plastic containers are generally recommend.

3. Keep away from fire sources: as chloroisobutyl ketone is flammable, it should be kept away from fire sources and high temperature environment, and avoid contact with oxidants, reducing agents, strong acids, strong alkalis and other chemicals.

Safety measures

The following safety precautions are required when storing and handling chloroisobutyl ketone:

1. Wearing protective equipment: Operators should wear protective gloves, protective glasses and protective clothing to avoid skin and eye contact with chloroisobutanone.

2. Ventilation: Good ventilation should be installed in storage and handling areas to prevent the accumulation of chloroisobutanone vapor in the air, causing health risks.

3. Emergency treatment: The warehouse shall be equipped with emergency treatment equipment, such as eye washer, sprinkler and fire extinguisher, to deal with possible accidents.

Conclusion

As an important chemical intermediate, chloroisobutyl ketone has been widely used in the fields of medicine, pesticide, coating and chemical reagent. Its production relies on upstream raw materials such as isobutyl ketone and chlorine, which are obtained by synthesis. Because of its active chemical nature and certain danger, it is necessary to strictly abide by safety regulations during storage and operation to ensure the safety of production and use. In the future, with the development of related industries, the application prospect of chloroisobutyl ketone will be broader.