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Glyoxal, also known as grass aldehyde (chemical formula: C2H2O2), is the simplest two aldehyde compounds. It is a colorless or pale yellow liquid at room temperature with a pungent odor. Glyoxal is highly reactive and easily reacts with water, alcohols and amines to form the corresponding adducts and condensates. It is easy to oxidize in the air to produce acetic acid and other by-products, so it needs to be operated under the protection of inert gas.
Glyoxal has a molecular weight of 58.04g/mol, a boiling point of 51°C, a melting point of -14°C, and a density of 1.265g/cm³(20°C). Its chemical properties are active and can react with a variety of compounds, such as reacting with ammonia to generate ethylenediamine, reacting with hydrogen sulfide to generate sulfurized glyoxal, etc. It can be polymerized to generate dimers or trimers, further enhancing its wide range of applications.
Glyoxal has a variety of uses in the chemical industry. It is an important raw material for the production of pharmaceutical intermediates, such as antibiotics, antiviral drugs, anti-cancer drugs and so on. Glyoxal is also used in the production of a variety of organic synthetic materials, such as resins, plastics, dyes and fungicides. In agriculture, it is used as an ingredient in herbicides and plant growth regulators. In the textile and leather industry, it is used as a modifier and crosslinking agent to enhance the strength and durability of the product.
There are two main methods for the production of glyoxal: ethanol oxidation and acetylene hydration. In the ethanol oxidation method, ethanol is oxidized to produce glyoxal under the action of a catalyst; in the acetylene hydration method, acetylene and water are hydrated under acidic conditions to produce glyoxal. Upstream feedstocks include ethanol, acetylene, hydrogen, oxygen, etc. Downstream products cover a wide range, from pharmaceutical intermediates to organic synthetic materials, glyoxal derivatives in different fields play an important role.
Since glyoxal is highly reactive and oxidizing, its storage requires special attention. Glyoxal should be stored in a closed container, avoid contact with air, to prevent oxidation and deterioration. The storage environment should be a cool, dry, well-ventilated place, and the temperature should be controlled within the low temperature range. Glyoxal should be kept away from fire, heat and chemicals such as oxidants and reductants to prevent dangerous reactions. Operators should wear protective equipment such as gloves, goggles and protective clothing when exposed to glyoxal to avoid health hazards from inhalation or skin contact.
The market demand for glyoxal mainly comes from the fields of medicine, agriculture and chemical industry. With the rapid development of the pharmaceutical industry, the demand for glyoxal as an intermediate is also increasing. With the increasingly stringent environmental regulations, glyoxal has broad application prospects in agriculture, especially as a green chemical and plant growth regulator. The demand for new materials and new technologies in the chemical industry also provides a broad space for the application of glyoxal.
Although glyoxal is widely used in industry, its toxicity and environmental impact cannot be ignored. Glyoxal is a strong irritant to the eyes, skin and respiratory system, and inhalation of high concentrations of vapor can lead to poisoning. Therefore, in the process of production and use, we must strictly abide by the safety operation procedures and take effective protective measures. Waste disposal also needs to meet environmental requirements to avoid environmental pollution.
As an important chemical raw material, glyoxal plays an important role in the fields of medicine, agriculture and chemical industry because of its active chemical properties and wide application prospect. Its high activity also poses storage and use challenges, requiring strict safety management and environmental protection measures. In the future, with the advancement of science and technology and the expansion of application fields, the market demand and application prospects of glyoxal will be broader, bringing new opportunities for the development of related industries.
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