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[Chemical Knowledge]：Detection Method and Analysis Technology of Diethylene Glycol

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Diethylene glycol, as an important chemical raw material, is widely used in many industrial fields, such as cosmetics, medicine, coatings, plastics and so on. The safety and purity of diethylene glycol are critical to product quality. Therefore, accurate and rapid detection and analysis of the content of diethylene glycol has become one of the important topics in related industries.

The traditional chemical analysis method is one of the earliest methods used in the detection of diethylene glycol. This method uses chemical reactions, using certain specific reagents to react with diethylene glycol to produce observable color changes or precipitates for qualitative and quantitative analysis. For example, the classical iodine titration method can calculate the content of diethylene glycol according to the amount of iodine remaining after the reaction by titrating a certain amount of iodine into a solution containing diethylene glycol. Although the traditional chemical analysis method has certain accuracy, its operation is cumbersome, time-consuming and easy to be affected by the operator's technical level, which can not meet the needs of modern industry for fast and efficient detection.

With the development of science and technology, instrument detection method has gradually become the mainstream of diethylene glycol detection. Among them, chromatography and spectroscopy are one of the more widely used instrument detection techniques. Chromatography mainly includes gas chromatography (GC) and liquid chromatography (LC). Gas chromatography uses the distribution coefficient between the stationary phase and the mobile phase to separate and detect the sample molecules through the gas phase transmission of the sample, which has the advantages of good separation effect and high sensitivity. Liquid chromatography, on the other hand, dissolves the sample in the stationary phase and the mobile phase, and uses the partition coefficients of different substances in the stationary phase and the mobile phase to separate and detect, which is suitable for the solubility of the sample. Spectroscopy mainly includes ultraviolet-visible absorption spectroscopy, infrared spectroscopy, etc., which are detected and analyzed by the absorption or scattering of light of a specific wavelength by a sample. These instrument detection methods have the advantages of simple operation, high degree of automation and good accuracy, and have become the mainstream technology of diethylene glycol detection.

In addition to traditional chemical analysis and instrument detection methods, in recent years, some new detection technologies have also emerged in the field of diethylene glycol detection. Among them, biosensor technology is an emerging technology that has attracted much attention. The biosensor uses the specific recognition effect of the biomolecule on the target molecule, binds the target molecule to the biological element (such as enzyme, antibody, etc.) on the biosensor, and detects the target molecule by measuring the signal change after the biological element binds to the target molecule. Compared with traditional chemical analysis and instrument detection methods, biosensor technology has the advantages of rapid detection, high sensitivity and good selectivity, and does not require complex pretreatment steps, which is suitable for the detection of complex samples.

In addition to biosensor technology, nanomaterials also show great potential in the field of diethylene glycol detection. Nanomaterials have special physical and chemical properties and can be used to construct high-sensitivity and high-selectivity sensors. For example, the introduction of nanomaterials such as gold nanoparticles and carbon nanotubes can enhance the detection performance of the sensor for diethylene glycol and improve the detection sensitivity and accuracy.

With the continuous progress of science and technology, the detection methods and analysis techniques of diethylene glycol are constantly updated and improved. From traditional chemical analysis to modern instrument detection, to new biosensor technology and nanomaterial applications, the continuous emergence of various methods and technologies will provide more choices and possibilities for the detection of diethylene glycol, and provide strong support for the development and progress of related fields.

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