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[Chemical Knowledge]：Detection Method and Analysis Technology of Triethylene Glycol

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As an important organic synthesis intermediate, triethylene glycol has a wide range of applications in chemical, pharmaceutical, pesticide and other fields. Because of its special structure, the traditional detection methods have many limitations, so it is very important to develop efficient and accurate detection methods and analysis techniques to ensure product quality and production safety.

In the detection and analysis of diethylene glycol, the commonly used methods include chromatography, mass spectrometry, spectroscopy and so on. Chromatography mainly includes gas chromatography and liquid chromatography two types. Gas chromatography separates and quantifies the target compounds by the distribution difference of the sample under the action of the stationary phase and the mobile phase, which has the advantages of good separation effect and high sensitivity, but it needs sample pretreatment and is not suitable for the compounds with large molecular weight. The principle of liquid chromatography can overcome some shortcomings of gas chromatography, and the separation effect of polar substances is better. The mass spectrometry method is to determine the composition and structure of the sample by mass analysis and combining the mass spectrometry characteristics of the sample, which has the characteristics of high sensitivity and high resolution, but requires expensive equipment and complex operation technology.

Spectroscopy is also widely used in the detection and analysis of triethylene glycol. Infrared spectroscopy can determine the molecular structure of a sample based on the vibrational frequencies of different functional groups by interacting with infrared light of specific wavelengths. Ultraviolet-visible absorption spectrum law is the use of the sample to a specific wavelength of light absorption to determine its concentration or reaction kinetics and other parameters. These spectroscopic methods not only have the characteristics of simple operation and fast analysis speed, but also can carry out non-destructive analysis of samples and maintain the integrity of samples.

In addition to the traditional detection methods, in recent years, with the continuous development of science and technology, some new detection technology has been gradually introduced to the analysis of triethylene glycol. For example, the electrochemical detection technology based on the electrochemical principle realizes the quantitative analysis of the target compound by measuring the electrochemical signal of the sample on the electrode, which has the advantages of simple operation, fast sensitivity and low cost, and is suitable for the analysis of complex samples. Immunoassay technology based on immunological principles is also widely used in the field of biomedicine, which realizes the detection and quantitative analysis of target compounds through the binding reaction of antibodies and specific antigens, and has the characteristics of high sensitivity and high specificity.

In addition to selecting the appropriate detection method, sample pretreatment is also one of the important factors affecting the detection results. Common sample pretreatment methods include extraction, concentration, purification and other steps to reduce the influence of background interference substances and improve the detection sensitivity and accuracy of target compounds.

The detection method and analysis technology of diethylene glycol involve many aspects, and it is necessary to select the appropriate method and technology according to the specific situation, and to carry out reasonable sample pretreatment in practical application in combination with the sample characteristics to ensure the accuracy and reliability of the test results. With the continuous progress of science and technology, it is believed that more innovative methods and technologies will be introduced in the field of detection and analysis of triethylene glycol in the future, providing more reliable technical support for the development and application of related fields.

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