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[Chemical Knowledge]：Detection method and analysis technology of 2,6-di-tert-butyl-p-cresol

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As an important antioxidant, 2,6-di-tert-butyl-p-cresol (BHT) is widely used in food, cosmetics and other fields. As people pay more and more attention to food safety and environmental pollution, the detection and analysis technology of BHT has become more and more important. At present, the detection methods for BHT mainly include chromatography, mass spectrometry, spectroscopy and so on, among which chromatography is the most widely used.

Chromatography is a technical means of separating compounds in a sample and determining their concentrations, including gas chromatography (GC) and liquid chromatography (LC). In the detection of BHT, gas chromatography is commonly used. The basic principle is to use the sample molecules in the gas phase carrier gas phase mobile phase distribution coefficient is different, through the separation of the chromatographic column, the different compounds are separated, and then through the detector to detect its concentration. Gas chromatography has the advantages of fast analysis speed, good separation effect and high detection sensitivity, so it is widely used in the detection and analysis of BHT.

With the continuous progress of science and technology, modern chromatography has also made breakthroughs in the detection of BHT. For example, by combining gas chromatography and mass spectrometry (GC-MS), the presence of BHT can be more accurately identified and its structure and concentration can be further determined. Mass spectrometry can provide information such as molecular weight and fragment pattern of compounds, so as to identify and quantify BHT more accurately.

Spectroscopy is also one of the important means of BHT detection. Spectroscopy is based on the analysis of the absorption or emission characteristics of a compound at a specific wavelength, and commonly used include ultraviolet-visible spectroscopy (UV-Vis) and infrared spectroscopy (IR). By measuring the absorption of BHT at specific wavelengths, its concentration can be inferred indirectly. Spectroscopy has the advantages of simple operation and less sample pretreatment, and is especially suitable for the rapid analysis of large quantities of samples.

The detection method and analysis technology of 2,6-di-tert-butyl-p-cresol are of great significance in modern scientific research and industrial production. By continuously optimizing the existing technology and combining the application of new analytical methods, we can more accurately detect the presence and concentration of BHT, and provide strong support for ensuring food safety, environmental protection and other fields.

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