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[Chemical Knowledge]：The correct use of butyl lithium and precautions

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Among the chemical reagents, butyl lithium is a commonly used organolithium reagent, which is often used in organic synthesis reactions. Butyl lithium is a very active reagent with strong reducibility and alkalinity, so extra care is required during use. The following is the correct use of butyl lithium and precautions:

1. Low temperature storage: Butyl lithium is a very easy oxidation reagent, so low temperature storage is required before use, and the common storage temperature is below -78 degrees Celsius. During storage and use, it is necessary to avoid exposure to air or moisture.

2. Note: When operating butyl lithium, you need to wear protective equipment, including lab clothes, gloves, goggles, etc. At the same time, it is necessary to operate in a well-ventilated laboratory environment to avoid the production of toxic gases.

3. Addition reaction: When butyl lithium needs to be added to the reaction system, an anhydrous solvent needs to be used, and butyl lithium needs to be slowly dropped in very small droplets. After the addition, it is necessary to wait for a period of time to allow the reaction to proceed smoothly.

4. waste treatment: after the end of the experiment, the unused butyl lithium needs to be treated according to the prescribed waste treatment method to avoid pollution to the environment.

The correct use of butyl lithium needs to follow strict operating procedures, and at the same time, it is necessary to pay full attention to safety matters to avoid accidents. Only in strict compliance with the operating procedures and have a wealth of experimental experience, in order to safely use butyl lithium, to ensure the smooth progress of the experiment. I hope the students in the chemistry laboratory can keep these precautions in mind and do a good job in laboratory safety.

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