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[Chemical Knowledge]：Medical common sense: the difference between irbesartan tablets and enalapril

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Irbesartan tablets and enalapril are commonly used antihypertensive drugs, often used in the treatment of hypertension. Although they are all antihypertensive drugs, there are some differences in their mechanism of action and pharmacological characteristics.

1. mechanism of action

irbesartan tablets belong to angiotensin II receptor antagonist, by blocking angiotensin II receptor, can expand peripheral blood vessels, lower blood pressure, reduce the burden on the heart. Enalapril is an angiotensin converting enzyme inhibitor, which inhibits the activity of the enzyme that converts angiotensin I into angiotensin II, thereby reducing the vasoconstriction effect of angiotensin II and achieving the effect of lowering blood pressure.

2. indications

irbesartan tablets are suitable for the treatment of essential hypertension and can also be used to improve the symptoms of patients with heart failure. In addition to the treatment of primary hypertension, enalapril can also be used for hypertension caused by renal insufficiency.

3. Usage and Dosage

Irbesartan Tablets The general dose is taken orally once a day, usually the starting dose is 150 mg, and the dose can be adjusted according to the condition. The usual dose of enalapril is taken orally once a day with a starting dose of 2.5 mg, and the dose is adjusted with the disease. If a diuretic is used at the same time, the dose may be adjusted.

4. side effects

the common side effects of irbesartan tablets include dizziness, fatigue, frequent urination and other symptoms, a small number of patients may have rash, hypokalemia and other adverse reactions. The common side effects of enalapril include cough, headache, diarrhea, etc. A few patients may have skin rash, abnormal liver function and other adverse reactions.

To sum up, although irbesartan tablets and enalapril are antihypertensive drugs, there are some differences in their mechanism of action, indications, dosage and side effects. Therefore, in the choice of the use of drugs, should be based on the specific circumstances and the doctor's recommendations for reasonable selection and use.

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