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[Chemical Knowledge]：Quinidine and quinine are not the same, do you understand?

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Quinidine and quinine are two common drugs that are often used to treat heart disease and other related conditions. Although they have similar names, in fact they have some obvious differences in composition, function and use.

let's find out about quinidine. Quinidine is an anti-arrhythmic drug used primarily to treat atrial fibrillation and other arrhythmias. It belongs to calcium antagonists, by inhibiting the calcium ions in myocardial cells into the cell, thereby slowing down the heart rate and reducing cardiac contractility. In addition, quinidine also has the effect of expanding coronary arteries, can increase the blood supply of the heart, improve the symptoms of myocardial ischemia.

Quinine, by contrast, is an antimalarial and antiarrhythmic drug. It is mainly used to treat malaria and to prevent the recurrence of malaria in the central nervous system. The mechanism of action of quinine is to slow down the electrical conduction velocity of the heart by affecting the electrical activity of nerve cells, so as to achieve the effect of inhibiting arrhythmia.

In addition, quinine also has a sedative effect, can be used to treat insomnia, anxiety and depression symptoms. This is because quinine can inhibit the excitability of the central nervous system, producing a calming effect.

Although quinidine and quinine have different pharmacological effects and uses, in some cases, they can have some common indications. For example, both can be used to treat angina symptoms caused by arrhythmias, reduce the load on the heart, and improve the quality of life of patients.

However, in the process of medication, we also need to pay attention to some adverse reactions. The common adverse effects of quinidine include hypotension, nausea, vomiting and aggravation of arrhythmia. Quinine, on the other hand, may cause gastrointestinal discomfort, dizziness and allergic reactions.

In general, quinidine and quinine are two drugs with similar uses but different mechanisms of action. Before using these drugs, patients should consult their doctor's advice and follow the doctor's instructions. In addition, pay attention to the adverse reactions and contraindications of drugs to ensure the safety and effectiveness of medication.

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