Phenol ketone products

Plastic rubber

Current Location： Home > News > Chemical Knowledge > The production and manufacturing method and process of brominated acetone.

[Chemical Knowledge]：The production and manufacturing method and process of brominated acetone.

Read： 507 Time：20months ago Source：Transform the World with Simplicity

The manufacturing method
of brominated acetone
1. Introduction

Brominated acetone is an important organic synthesis intermediate, widely used in the production of pharmaceuticals, pesticides, spices and other chemicals. This paper will introduce a manufacturing method of bromoacetone, which has the advantages of simple operation, high yield and good safety.

2. experimental principle

bromoacetone is produced by electrophilic substitution reaction between acetone and bromine under alkaline conditions. The reaction equation is as follows:

CH3COCH3 + Br2 → CH3COCH2Br + HBr

3. Experimental steps

1. Add acetone to the reactor, start stirring, and control the temperature at 10-15°C.
2. Slowly add aqueous sodium hydroxide to adjust the pH to basic.
3. Bromine is slowly added dropwise under stirring, and the dropping speed is controlled so that the reaction temperature does not exceed 25 ℃.
4. After the dropwise addition is completed, stirring is continued for 2-3 hours to allow the reaction to proceed sufficiently.
5. After completion of the reaction, the reaction mixture was poured into a separatory funnel and washed with water until neutral.
6. The organic phase was separated and dried over anhydrous sodium sulfate.
7. The bromoacetone product was collected by filtration and distillation.

4. Precautions

1. Bromine is highly corrosive, and protective equipment should be worn during operation to avoid contact with skin.
2. The temperature should be strictly controlled during the reaction to prevent side reactions caused by excessive temperature.
3. During the washing process, it is necessary to ensure that the washing is neutral to avoid alkaline impurities in the product.
4. Distillation needs to control the distillation speed to avoid product decomposition.

5. Experimental results and discussion

1. Experimental results

Bromoacetone manufactured by this method, the yield can reach more than 90%, the purity of the product can reach more than 98%.

2. Results Discussion

This method can effectively improve the yield of bromination reaction under alkaline conditions. At the same time, controlling the reaction temperature and pH value can avoid the occurrence of side reactions and improve the purity of the product. In addition, the method is simple, safe and suitable for industrial production.

6. Conclusion

This paper introduces a method for the manufacture of bromoacetone, which has the advantages of simple operation, high yield and good safety. Through experimental verification, the method can prepare high purity bromoacetone, which is suitable for industrial production.

Previous： Manufacturing method and process of fluorinated acetone

Next： Production and manufacturing method and process flow of iodinated acetone

News Categories