Current Location： Home > News > Chemical Knowledge > Production and manufacturing method and process of 4-heptanone

[Chemical Knowledge]：Production and manufacturing method and process of 4-heptanone

Read： 768 Time：20months ago Source：Transform the World with Simplicity

The manufacturing method
of 4-heptanone
1. Introduction

4-heptanone is an important organic chemical raw material, widely used in medicine, pesticides, spices, dyes and other fields. Therefore, it is of great practical significance to study the manufacturing method of 4-heptanone. This paper will introduce a method of preparing 4-heptanone from acetone and butyraldehyde through aldol condensation reaction and dehydrogenation reaction.

2. experimental raw materials and equipment

1. Raw materials: acetone, butyraldehyde
2. Equipment: stirred reactor, dehydrogenation reactor, condenser, fractionation tower and other

3. experimental steps

1. Aldol condensation reaction

In the stirred reactor, acetone and butyraldehyde are mixed at a molar ratio of 1:1, acidic catalyst is added, the temperature is raised to 60-80 ℃, and the reaction is carried out for 6-8 hours. During the reaction, the progress of the reaction was detected by sampling regularly. When the aldol condensation reaction was completed, the reaction was stopped.

2. Dehydrogenation reaction

The product obtained from the aldol condensation reaction is transferred to a dehydrogenation reactor, a dehydrogenation catalyst is added, the temperature is raised to 200-250 ° C., and the dehydrogenation reaction is carried out under a hydrogen atmosphere. During the reaction, the pressure of the system was kept stable, and the reaction progress was detected by sampling regularly. When the dehydrogenation reaction is completed, the reaction is stopped.

3. Product Separation and Purification

The gas in the dehydrogenation reactor is cooled by a condenser and the 4-heptanone product is separated by a fractionation column. Fractions of 4-heptanone were collected and further purified to obtain 4-heptanone of higher purity.

4. Experimental results and discussion

1. Experimental results

In this experiment, 4-heptanone was successfully prepared by aldol condensation reaction and dehydrogenation reaction, with a high yield and a purity of more than 95%.

2. Results Discussion

In the aldol condensation reaction, the type and amount of acid catalyst have a great influence on the reaction rate and selectivity. The experimental results show that a better reaction effect can be obtained by using appropriate amount of sulfuric acid as catalyst. In addition, the reaction temperature and time also need to be optimized according to the actual situation.

In the dehydrogenation reaction, the type and amount of dehydrogenation catalyst also have a great influence on the reaction rate and selectivity. The experimental results show that the appropriate amount of copper-zinc-aluminum catalyst can obtain better dehydrogenation effect. At the same time, keeping the system pressure stable and controlling the hydrogen flow rate are also the key factors for the dehydrogenation reaction.

5. conclusion

In this experiment, 4-heptanone was successfully prepared from acetone and butyraldehyde by aldol condensation reaction and dehydrogenation reaction. The experimental results show that the method has the advantages of high yield and high purity, and has a certain industrial application prospect. At the same time, this study also provides a new idea and method for the manufacture of 4-heptanone.

Previous： Manufacturing method and process of 3-heptanone

Next： Production and manufacturing method and process of 5-heptanone

News Categories