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Dimethyl malonate is an important organic chemical raw material, widely used in medicine, pesticides, spices, dyes and other fields. This article will detail the properties and uses of dimethyl malonate.
1. properties of dimethyl malonate
1. physical properties of
malonate dimethyl ester is a colorless transparent liquid, pungent odor. Relative density 1.073, melting point -48 ℃, boiling point 199.3 ℃, refractive index 1. 3697, flash point (open cup) 100 ℃. With ethanol, ether, acetone and benzene miscible, slightly soluble in water.
2. chemical properties of
malonic acid dimethyl ester with active methylene, heat decomposition into methyl ketone, acidic conditions into methyl ketone. Heating under alkaline conditions, can occur in the rearrangement reaction of crotonate. Dimethyl malonate can be transesterified with alcohols, amines and other compounds to generate the corresponding esters and amides.
two, dimethyl malonate use
1.
in the field of medicine dimethyl malonate in the field of medicine has a wide range of applications, can be used for the synthesis of antibacterial drugs, antineoplastic drugs, antiepileptic drugs and so on. For example, dimethyl malonate can be used to synthesize sulfonamides, which inhibit the growth of a variety of bacteria.
2.
in the field of pesticides Dimethyl malonate can be used to synthesize a variety of pesticides, such as insecticides, fungicides, etc. These pesticides have a good control effect on crop diseases and insect pests, and help to improve the yield and quality of crops.
3. perfume field
dimethyl malonate can be used for the synthesis of a variety of spices, such as food flavor, flavor, etc. These spices have a beautiful aroma and taste, can be widely used in food, cosmetics and other industries.
4.
in the field of dyes Dimethyl malonate can be used to synthesize a variety of dyes, such as acid dyes, direct dyes, etc. These dyes have good color and dyeing properties and can be used in textile, printing and dyeing industries.
In conclusion, dimethyl malonate, as an important organic chemical raw material, has a wide range of applications in the fields of medicine, pesticides, spices, dyes and so on.