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[Chemical Knowledge]：Properties and Uses of Cyclohexanone Oxime

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Cyclohexanone oxime is an important organic chemical raw material, widely used in medicine, pesticides, dyes and other fields. This article will detail the properties and uses of cyclohexanone oxime.

, the nature of cyclohexanone oxime

cyclohexanone oxime is a colorless or slightly yellow crystalline powder, with a strong pungent odor. It is easily soluble in organic solvents such as water and ethanol, but insoluble in non-polar solvents such as ether and benzene. Cyclohexanone oxime has good thermal stability, but it is prone to hydrolysis under acidic and alkaline conditions.

cyclohexanone oxime has important chemical reactivity and can undergo a variety of derivatization reactions. Among them, the most common reaction is the acylation reaction of cyclohexanone oxime with acid anhydride, acid chloride and other compounds to generate the corresponding cyclohexanone amide compounds. In addition, cyclohexanone oxime can also react with metal organic compounds such as Grignard reagents to generate corresponding alcohols.

2. the use of cyclohexanone oxime

1.

in the field of medicine Cyclohexanone oxime has a wide range of applications in the field of medicine, mainly for the production of anti-tuberculosis drugs, anti-inflammatory drugs, anti-tumor drugs. For example, cyclohexanone oxime can be used as a raw material to synthesize the anti-tuberculosis drug isoniazid, which has a strong inhibitory effect on Mycobacterium tuberculosis and is a first-line drug for the treatment of tuberculosis.

2.

in the field of pesticides Cyclohexanone oxime is also widely used in the field of pesticides, mainly for the production of fungicides, pesticides and other pesticides. For example, cyclohexanone oxime can be used as a raw material to synthesize a broad-spectrum fungicide prochloraz, which has excellent control effects on a variety of plant pathogens and is widely used in pest control of fruit trees, vegetables and other crops.

3.

in the field of dyes Cyclohexanone oxime also has important applications in the field of dyes, mainly for the production of cationic dyes, acid dyes, etc. For example, cyclohexanone oxime can be used as a raw material to synthesize cationic dye alkaline brilliant green, which has the characteristics of bright color and strong coloring power, and is widely used in dyeing wool, silk and other fabrics.

In short, cyclohexanone oxime as an important organic chemical raw material, has a wide range of applications in the field of medicine, pesticides, dyes and so on.

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