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[Chemical Knowledge]：Properties and Uses of Phosphorus Oxychloride

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Phosphorus oxychloride is a strong oxidizing and corrosive chemicals, widely used in chemical, pharmaceutical, pesticide and other fields. This article will detail the nature and use of phosphorus oxychloride.

1. properties

1. physical properties

phosphorus oxychloride is a colorless transparent liquid, pungent odor, volatile. It is insoluble in water, but can be miscible with many organic solvents, such as ethanol, ether, benzene and so on.

2. chemical properties

phosphorus oxychloride has strong oxidizing and corrosive, can react with many substances. It can react with metals, non-metals, organics, etc. to generate the corresponding phosphates and chlorides. At the same time, phosphorus oxychloride can also react with water to form phosphoric acid and hydrogen chloride.

2. uses

1. pharmaceutical intermediates

of phosphorus oxychloride can be used as pharmaceutical intermediates for the synthesis of some drugs. For example, it can react with amine compounds to generate the corresponding phosphoramide compounds, which have certain pharmacological activities and can be used as anticancer, antiviral and other drugs.

2. Pesticide Production

Phosphorus oxychloride can also be used in pesticide production, for example, it can react with alcohol compounds to generate the corresponding phosphate compounds, which can be used as insecticides, fungicides, etc.

3. organic synthesis

phosphorus oxychloride in organic synthesis also has a wide range of applications. It can be used as a chlorinating agent and oxidant, and participate in many organic reactions, such as Friedel-Crafts reaction, Ullman reaction and so on. At the same time, phosphorus oxychloride can also be used to synthesize some special phosphate compounds, which have a wide range of applications in materials, surfactants and other fields.

In conclusion, as an important chemical raw material, phosphorus oxychloride is widely used in medicine, pesticide, organic synthesis and other fields. In the use of the process need to pay attention to its strong oxidation and corrosion, do a good job of safety protection measures.

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