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[Chemical Knowledge]：Properties and uses of ethyl formate

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Ethyl formate is a widely used organic compound and plays an important role in the field of chemical production raw materials. This article will detail the nature of ethyl formate, production methods, safety and use of knowledge.

1. the nature of ethyl formate

ethyl formate is a colorless and transparent liquid with a pungent odor. Its molecular formula is C3H6O2, and its structure is HCOOC2H5. Ethyl formate has a high boiling point of 53.5°C and a density of 0.922g/cm3. It is insoluble in water, but can be miscible with organic solvents such as alcohols and ethers. In addition, ethyl formate is flammable and toxic, so open flames and high temperatures should be avoided, and safety during storage and use should be paid attention.

2. ethyl formate production method

ethyl formate production method mainly has two kinds of esterification and reduction method. Esterification method is the esterification reaction of formic acid and ethanol under the action of acidic catalyst to generate ethyl formate and water. The reduction law is to obtain ethyl formate by reducing methyl formate or ethyl formate salt. Different production methods have different advantages and disadvantages, and the appropriate production process can be selected according to the actual situation.

3. the safety
of ethyl formate. Ethyl
formate has certain toxicity and flammability, so it is necessary to pay attention to safety during storage, transportation and use. Contact with open flame and high temperature should be avoided, and sealing measures should be taken to prevent leakage. Operators should wear protective equipment to avoid contact with ethyl formate.

4. the use of ethyl formate

of ethyl formate in the field of chemical production raw materials has a wide range of uses, mainly used in the following aspects:

1. solvent: ethyl formate can be used as a solvent for coatings, inks, adhesives and other fields. It has good solubility and volatility, can improve the leveling and drying of the coating, and can reduce the viscosity of the ink and improve the printing effect.
2. organic synthesis intermediate: ethyl formate can be used as an organic synthesis intermediate for the synthesis of various esters, amides, ketones and other compounds. For example, it can react with an amine compound to obtain an amide compound, react with an aldehyde compound to obtain a ketone compound, etc.
3. Fragrance manufacturing: Ethyl formate has a pleasant fruity aroma and can be used to make fragrances and essences. In the food industry, it is often used as a food additive to regulate the taste and aroma of food.
4. pharmaceutical intermediates: ethyl formate can be used as pharmaceutical intermediates for the synthesis of antibacterial drugs, anti-inflammatory drugs and other drugs. For example, it can be used to synthesize the non-steroidal anti-inflammatory drug ibuprofen, etc.

In short, ethyl formate has a wide range of applications in the field of chemical production raw materials, and provides important support for product manufacturing in various fields.

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