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[Chemical Knowledge]：Properties and Uses of o-Chloroaniline

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O-chloroaniline is an important chemical raw material, which has a wide range of applications in the field of chemical production. This article will detail the nature of o-chloroaniline, production methods, safety and use of knowledge.

1. the properties of o-chloroaniline

o-chloroaniline is an organic compound with a chemical formula of C6H6ClN and a molecular weight of 127.57. It is a colorless or yellowish oily liquid with a strong pungent odor. o-Chloroaniline has a melting point of -8°C, a boiling point of 202°C and a density of 1.26g/cm3. It is insoluble in water, but soluble in alcohol, ether and other organic solvents. o-Chloroaniline is basic and can react with acids to form salts.

2. o-chloroaniline production methods

o-chloroaniline production methods are mainly the following:

1. aniline chlorination: aniline and chlorine in the presence of a catalyst for chlorination reaction, generate o-chloroaniline and p-chloroaniline mixture, and then by distillation separation of pure o-chloroaniline.
2. Nitrobenzene reduction method: nitrobenzene is reduced to aniline, and then chlorinated to obtain o-chloroaniline.

3. the safety
of o-chloroaniline
o-chloroaniline has certain toxicity. Long-term exposure or inhalation can cause human body to have toxic symptoms, such as dizziness, headache, nausea, vomiting, etc. In addition, o-chloroaniline is also corrosive and irritating, and has an irritating effect on the eyes and skin. Therefore, strict attention should be paid to safety measures during production and use.

4. the use of o-chloroaniline

o-chloroaniline is an important chemical raw material, widely used in medicine, pesticides, dyes and other fields. The following are the main uses of o-chloroaniline:

1. Pharmaceutical intermediates: o-chloroaniline is the key intermediate of many pharmaceutical products, such as antibacterial drugs, anticancer drugs, anti-tuberculosis drugs, etc.
2. Pesticides: o-chloroaniline can be used in the manufacture of pesticides, fungicides and other pesticide products.
3. Dyes: o-chloroaniline can be used as a dye intermediate for the production of various dyes.

In short, as an important chemical raw material, o-chloroaniline plays an important role in the fields of medicine, pesticide, dye and so on. Understanding and mastering the properties, production methods, safety and use of o-chloroaniline is of great significance for the better application and development of o-chloroaniline. In the process of use, it is necessary to pay attention to safety measures to avoid harm to the human body and the environment.

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