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Trichloroacetone is an important raw material for chemical production, with unique properties and a wide range of uses. This article will detail the properties, production methods, safety and applications of trichloroacetone in different fields.
1. the nature of trichloroacetone
trichloroacetone is a colorless transparent liquid, pungent odor. Its molecular formula is C3HCl3O and its molecular weight is 163.4. Trichloroacetone has a strong ability to dissolve, can be dissolved in many organic solvents, such as ethanol, ether, acetone and so on. In addition, trichloroacetone also has a high boiling point and flash point, so it has good thermal stability and storage safety.
2. trichloroacetone production method
trichloroacetone production method mainly has two kinds: one is obtained by the reaction of acetone and chlorine, the other is obtained by the reaction of acetone and hypochlorite. Among them, acetone and chlorine reaction method is a more commonly used production method, the reaction equation is:
CH3COCH3 3Cl2 → CCl3COCCl3 3HCl
In this process, acetone and chlorine react under the action of a catalyst to generate trichloroacetone and hydrogen chloride. By controlling the reaction temperature and the type and amount of the catalyst, a higher yield of trichloroacetone can be obtained. The safety
of
3. trichloroacetone
trichloroacetone has certain toxicity and irritation, which can irritate eyes, skin and respiratory system. Therefore, in the process of production and use, it is necessary to strictly abide by the safety operation procedures and avoid contact with human body and food. In addition, trichloroacetone is also flammable, in case of open flame, high heat or oxidant contact, there is a risk of combustion and explosion. Therefore, it is necessary to pay attention to fire prevention and sun protection measures during storage and transportation.
4. trichloroacetone use
1. pharmaceutical intermediates
trichloroacetone is an important pharmaceutical intermediates, can be used for the synthesis of a variety of drugs, such as antibacterial drugs, anti-inflammatory drugs, anticancer drugs. For example, trichloroacetone can be used as a starting material to synthesize procaine hydrochloride, which is a commonly used local anesthetic.
2. Pesticide intermediate
Trichloroacetone can also be used to synthesize pesticides, such as insecticides, fungicides, etc. For example, trichloroacetone can be used as a raw material to synthesize imidacloprid, which is an efficient and low-toxic insecticide that is widely used in agricultural and sanitary pest control.
3. Organic synthesis raw material
as an important organic synthesis raw material, can be used to synthesize a variety of organic compounds, such as ketones, esters, ethers and so on. These compounds are widely used in plastics, rubber, coatings and other fields.
In conclusion, trichloroacetone, as an important raw material for chemical production, has a wide range of uses and good market prospects. It is necessary to pay attention to safety issues during production and use, strictly abide by operating procedures, and ensure product quality and production safety.