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[Chemical Knowledge]：Properties and Uses of Tetrahydrofurfuryl Alcohol

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Tetrahydrofurfuryl alcohol (THF) is an important organic chemical raw material, which is widely used in medicine, pesticides, spices, plastics and solvents. This article will detail the properties and uses of tetrahydrofurfuryl alcohol.

1. the properties of tetrahydrofurfuryl alcohol

1. physical properties
tetrahydrofurfuryl alcohol is a colorless transparent liquid, with similar ether odor. Its boiling point is 100.8 ℃, melting point is -108.5 ℃, relative density is 0.986(20/4 ℃), refractive index is 1.4472, flash point is 12 ℃ (closed cup), ignition point is 321 ℃. Tetrahydrofurfuryl alcohol is insoluble in water, but miscible with ethanol, ether, acetone, benzene and other organic solvents.

2. chemical properties
tetrahydrofurfuryl alcohol has certain chemical stability, but it is easy to react under strong acid and strong alkali conditions. It can be with aldehydes, ketones, esters and other compounds for addition reaction to generate the corresponding alcohols. In addition, tetrahydrofurfuryl alcohol can also occur oxidation, reduction, esterification, etherification and other reactions.

2. the use of tetrahydrofurfuryl alcohol

1
in the field of medicine tetrahydrofurfuryl alcohol has a wide range of applications in the field of medicine, commonly used as intermediates in the synthesis of drugs. It can be used for the synthesis of antibacterial drugs, anti-tumor drugs, antiviral drugs and other drugs. For example, tetrahydrofurfuryl alcohol can be used as a raw material for the synthesis of cyclosporine, which is an immunosuppressant and can be used for anti-rejection after organ transplantation.

2. Pesticide Field
In the field of pesticides, tetrahydrofurfuryl alcohol is commonly used in the synthesis of insecticides, fungicides and herbicides. For example, it can be used as an intermediate for the synthesis of imidacloprid, which is a broad-spectrum, high-efficiency, and low-toxicity insecticide, which is widely used to control various crop pests.

3.
in the field of fragrances Tetrahydrofurfuryl alcohol has a special fragrance and can be used to prepare flavors as food additives or raw materials for daily chemicals. It can be used to make fruit flavors, floral flavors, etc., to add a pleasant aroma to food or daily necessities.

4.
in the field of plastics In the field of plastics, tetrahydrofurfuryl alcohol can be used as a plasticizer to improve the processing performance and flexibility of plastics. It can also be used to synthesize some special polymers, such as polytetrahydrofuran.

5. Solvent Field
Tetrahydrofurfuryl alcohol is an excellent solvent that can be used to dissolve many organic substances. It has a wide range of applications in the fields of inks, coatings, adhesives, etc., and can improve the fluidity and uniformity of products.

In conclusion, as an important organic chemical raw material, tetrahydrofurfuryl alcohol is widely used in the fields of medicine, pesticide, spice, plastic and solvent. With the continuous development of science and technology, the application field of tetrahydrofurfuryl alcohol will continue to expand.

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