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The nature and use
of tetrahydrofuran in the field of raw materials for chemical production
Abstract:
This paper introduces in detail the nature and use of tetrahydrofuran in the field of raw materials for chemical production. The physical properties, chemical properties, safety and production methods of tetrahydrofuran were discussed, and its application in solvents, synthetic materials, pharmaceutical intermediates and other fields was described.
1. Introduction
Tetrahydrofuran is an important organic compound, widely used in the field of chemical production raw materials. Understanding its nature and use is of great significance for improving chemical production efficiency and product quality.
2. the nature of tetrahydrofuran
1. physical properties: tetrahydrofuran is a colorless transparent liquid, with similar ether odor. It has a high boiling point, flash point and ignition point, and has good solubility and fluidity.
2. Chemical properties: Tetrahydrofuran has high chemical stability and is not easy to occur oxidation, reduction and other reactions. At the same time, it also has good acid and alkali resistance.
3. the use of tetrahydrofuran
1. Solvent: Tetrahydrofuran is an excellent solvent, can be used to dissolve many organic and inorganic substances. It is widely used in coatings, inks, adhesives and other fields.
2. Synthetic materials: Tetrahydrofuran can be used as a monomer to participate in the polymerization reaction to generate polymer materials such as polytetrahydrofuran. These materials have excellent heat resistance, oxidation resistance and chemical resistance, and can be used to manufacture seals, pipes, etc.
3. Pharmaceutical intermediates: Tetrahydrofuran is often used as an intermediate for synthetic drugs in the pharmaceutical industry, and can be used to produce anti-tumor drugs, antibacterial drugs, etc.
4. of tetrahydrofuran production methods
industry commonly used tetrahydrofuran production methods are mainly the following:
1. Acetylene method: acetylene and formaldehyde as raw materials, in the presence of a catalyst for addition reaction to obtain 1,4-butynediol, and then by catalytic hydrogenation to produce tetrahydrofuran.
2. Propylene method: using propylene, water and carbon monoxide as raw materials, 1,4-butanediol is prepared by catalytic oxidation, hydrogenation dehydration and other steps, and then tetrahydrofuran is obtained by dehydrogenation cyclization. Safety
of
5. Tetrahydrofuran Although
tetrahydrofuran has many excellent properties and a wide range of uses, it also has certain safety problems. It is irritating to the skin and eyes, and long-term exposure may cause skin degreasing and eye damage. In addition, tetrahydrofuran also has a certain toxicity, inhalation of high concentrations of tetrahydrofuran vapor may lead to poisoning. Therefore, in the process of production and use, it is necessary to strictly abide by the safety operation procedures to ensure the health and safety of the staff.
6. conclusion
tetrahydrofuran has a wide range of applications in the field of chemical production raw materials, and understanding its properties and uses is of great significance to improve the production efficiency and product quality of chemical products. In the process of use, we need to pay attention to its safety, strictly abide by the safety operation procedures, and ensure the health and safety of the staff. With the continuous progress of science and technology and the continuous growth of demand, tetrahydrofuran will be more widely used in the future and play a greater role in the development of the chemical industry.