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[Chemical Knowledge]：Explore the principle of liquid-liquid extraction

Read： 651 Time：14months ago Source：Transform the World with Simplicity

Liquid-liquid extraction is one of the commonly used separation technologies in chemical processes, which can separate compounds of different polarities and concentrate one of them in a specific medium. Because of its advantages of good separation effect, simple operation and low cost, the technology is widely used in biological pharmaceutical, chemical and other fields. So, what is the principle of liquid-liquid extraction?

liquid-liquid extraction is separated by the difference in partition coefficient between the two liquid phases (usually water and organic solvents). The distribution coefficient refers to the distribution ratio of the compound in the two liquid phases, and its size is related to the polarity of the compound and the compatibility of the two liquid phases. In the process of

liquid-liquid extraction, the two liquid phases are mixed together to form a mixture of a certain proportion, and the compounds are then distributed into the mixture. Since the distribution coefficients of the compounds between the mixed liquid and the separation liquid are different, the separation of the compounds can be achieved when the distribution coefficients between the mixed liquid and the separation liquid reach equilibrium. In this case, a liquid containing the specific compound can be obtained by separating the two liquid phases. The advantages of

liquid-liquid extraction also include that it does not require advanced equipment, is suitable for large-scale separation, and can improve product purity. It can be used not only for the separation of organic compounds, but also for the separation of biopharmaceuticals, medicinal chemistry and other fields. In pharmaceutical preparations, the target drug can be obtained by liquid-liquid extraction technology to improve the purity and efficacy of the drug; in the production process of some chemical products, the impurities can be removed by the separation of liquid-liquid extraction to improve the quality of the product.

liquid-liquid extraction technology as a simple and efficient separation method, has been widely used in various fields. For chemicals, biopharmaceuticals, and other industries that require high-purity substances, liquid-liquid extraction can not only improve product quality, but also reduce production costs. If readers are interested in liquid-liquid extraction technology, they can find more relevant information and carry out practical operations in the professional field.

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