Phenol ketone products

Plastic rubber

Current Location： Home > News > Chemical Knowledge > Production process and preparation method of acetylacetone

[Chemical Knowledge]：Production process and preparation method of acetylacetone

Read： 646 Time：18months ago Source：Transform the World with Simplicity

Acetylacetone is a commonly used organic synthetic compound, which is widely used as a ligand in the research field, as well as in the industrial fields such as medicine and perfume. This article will introduce the production process and preparation method of acetylacetone. The most commonly used method for the synthesis of

acetylacetone is by the reaction of an acetate ester with an acetylation reagent, which is also known as the acetic acid method. The production process of

acetic acid method is as follows:
1. Obtain acetate raw materials, such as propyl acetate;
2. In an acetylation reactor, propyl acetate and an acetylation reagent are added to the reactor to complete the esterification reaction through the action of a catalyst;
3. After the reaction is completed, the organic solvent and the reaction by-products are separated by water or other methods;
4. Acetylacetone is purified by distillation or purification.

Another method for preparing acetylacetone is the diketone method. This process uses phenols, aldehydes or other carbonyl-containing compounds as starting materials to obtain acetylacetone by ketal reaction. Since the reaction involves an intermediate of the oxydone, this method is also referred to as the oxydone method. The production process of the

oxyketone method is as follows:
1. Obtaining raw materials containing carbonyl groups, such as phenol and acetone;
2. In the reactor, phenol and acetone are added, and ketal agent and catalyst are added to start ketal reaction;
3. After the reaction, the organic solvent and reaction by-products are separated by water or other methods;
4. Acetylacetone is purified by distillation or adsorbent.

In addition to the above two methods for preparing acetylacetone, there are other methods, such as catalytic hydrogenation. Different methods have their own advantages and disadvantages, and their applicability needs to be evaluated before use.

Generally speaking, the difficulty of acetylacetone production process lies in the selection of catalyst and the control of reaction conditions. The former needs to choose a catalyst that can effectively reduce the activation energy of the reaction, and the latter needs to react under oxygen-free or oxygen-less conditions to avoid side reactions. In addition, the separation and purification after the reaction also requires certain skills and equipment support.

summary, acetylacetone is a compound with a wide range of applications in research and industry. Methods for preparing acetylacetone mainly include acetic acid method and oxyketone method, and there are other methods. In the production process, it is necessary to pay attention to the problems of catalyst, reaction conditions and separation and purification to ensure production quality and cost control.