4-tert-Butylphenol (4-tert-Butylphenol)

It is used for the synthesis of antioxidant; P-tert-butyl phenol is used for the synthesis of acaricide propargite on pesticides, and it is also the raw material of the new fungicide spironamine (spiroxamine). It has antioxidant properties and can be used as stabilizer for rubber, soap, hydrochloric ether and nitrocellulose; It is medicine (insecticide)..

Reference dosage of 4-tert-butyl phenol (98-54-4): trace amount is used in daily chemical Essence. Although the dosage is very small, it has been applied for more than 70 years. The concentration of this product in the final daily chemical product is generally 0 in soap. 01%~ 0.1%; Perfume class 0.08% ~ 0.1%; Cream and water class 0.003% ~ 0.03%; Washing supplies 0.001%~ 0.01%. Preparation method: it is obtained by heating phenol and isobutene in the presence of zinc chloride or by heating tert-butyl alcohol with sulfuric acid as catalyst at 100℃. The crude product can be crystallized twice with ethanol to obtain p-tert-butyl phenol. Stability and reaction activity: prohibited compounds: acyl chloride, oxidant, anhydride, base, copper. Toxicology data: acute toxicity: 2520 mg/kg (rabbit percutaneous) LD50:3250 mg/kg (rat oral). Haxards summarizing: health hazards: This product is allergic to skin, and skin contact can cause dermatitis. It can stimulate eyes, skin and mucosa. Repeated contact with this product can cause white spot disease. White spot can occur on the skin of non-exposed parts except the exposed part of the skin, sometimes showing symmetry. Animal experiments have proved that exposure to this product through mouth or respiratory tract can cause leukoderma. Explosive danger: This product is flammable, pungent, toxic and sensitizing. First aid measures: 1. Eye contact: lift the eyelid and rinse with flowing water or normal saline. See a doctor. 2. Skin Contact: remove contaminated clothes and rinse the skin thoroughly with soap and water. Eating: drink enough warm water to induce vomiting. See a doctor. 3. Inhalation: keep respiratory tract unobstructed. Quickly leave the scene to the fresh air. If you have difficulty breathing, give oxygen. If breathing stops, perform artificial respiration immediately. And seek medical treatment in time. Fire protection measures: 1. Dangerous characteristics: in case of open flame, high heat combustible. It is decomposed by high heat and releases irritant smoke. It can react strongly with oxidant. 2. Harmful combustion products: carbon monoxide and carbon dioxide. 3. Fire extinguishing method: use carbon dioxide, dry powder, foam and sand to put out fire. Emergency treatment of leakage: 1. Emergency treatment: cut off the fire source. It is recommended that emergency personnel wear dust masks (full face mask) and anti-virus clothing. Isolate leakage contaminated areas and restrict access. 2. Small leakage: collect it in a dry, clean and covered container with a clean shovel. 3. Large amount of leakage: collect and recycle or transport to waste disposal sites for disposal. ? Precautions for operation: operators must receive special training and strictly abide by the operating procedures. Stay away from fire and heat sources, and smoking is strictly prohibited in the workplace. It is recommended that operators wear self-priming filter dust masks, chemical safety protective glasses, anti-virus penetration overalls, and rubber gloves. Use explosion-proof ventilation system and equipment. Close operation, pay attention to ventilation. Avoid dust generation. Avoid contact with oxidants and bases. Light loading and unloading should be carried to prevent the packaging and containers from being damaged. Equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. The empty container may contain harmful substances. Storage precautions: keep away from fire and heat source. The package is sealed. Store in a cool and ventilated warehouse. Equipped with corresponding varieties and quantities of fire fighting equipment. It should be stored separately with alkali, oxidant and edible chemicals, and should not be mixed. The storage area should be equipped with appropriate materials to accommodate leaks. Packing method: Threads band glass bottles, iron cover pressure mouth glass bottles, plastic bottles or metal barrels (CANs) outside ordinary wooden boxes; Plastic bags or two layers Kraft paper bag outside full opening or middle opening steel barrel; Threads band glass bottles, plastic bottles or tinned steel sheet barrels (CANs) are covered with bottom plate lattice boxes, fiber board case or plywood boxes. Precautions for transportation: it is strictly prohibited to mix with acids, oxidants, food and food additives. Before transportation, check whether the packaging container is complete and sealed. During transportation, ensure that the container does not leak, fall, collapse or damage. During transportation, it should be protected from exposure, rain and high-temperature resistant. Shipping Information: Dangerous Goods Code: 61701;UN number: 2229; Packing Category: 053; Customs code: 29071900. Disposal method: refer to relevant national and local laws and regulations before disposal. Incineration is recommended. Contact control/individual protection: 1. Engineering control: closed operation, pay attention to ventilation. 2. Respiratory system protection: When the dust concentration in the air exceeds the standard, wear a self-priming filter dust mask. 3. Eye protection: wear chemical safety protective glasses. 4. Body protection: wear anti-virus penetration work clothes. 5. Hand protection: wear rubber gloves. 6. Other protection: maintain good hygiene habits. After work, shower and dressing. Smoking, eating and drinking are prohibited at the work site. Store clothes contaminated by poison separately and use them after washing.