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[Chemical Knowledge]：Production and manufacturing method and process of 4-methyl -2-pentanone

Read： 1044 Time：19months ago Source：Transform the World with Simplicity

4-Methyl-2-pentanone (also known as methyl isobutyl ketone or MIBK) is an organic compound that is widely used as a raw material for chemical production. The following are several common 4-methyl -2-pentanone manufacturing methods:

method one: acetone condensation method

1. mix acetone with sulfuric acid and react to generate hydrogen sulfate acetone.
2. Isopropanol is added to the reaction mixture to produce 4-methyl-2-pentanone and isopropyl hydrogen sulfate.
3. The acid in the reaction mixture is neutralized with lye, followed by distillation to isolate 4-methyl-2-pentanone.

method two: allyl alcohol method

1. mixing allyl alcohol with sulfuric acid, reaction generates allyl hydrogen sulfate.
2. Isopropanol is added to the reaction mixture to produce 4-methyl-2-pentanone and isopropyl hydrogen sulfate.
3. The acid in the reaction mixture is neutralized with lye, followed by distillation to isolate 4-methyl-2-pentanone.

method three: n-butanol method

1. will n-butanol mixed with sulfuric acid, reaction to generate n-butyl hydrogen sulfate.
2. Isopropanol is added to the reaction mixture to produce 4-methyl-2-pentanone and isopropyl hydrogen sulfate.
3. The acid in the reaction mixture is neutralized with lye, followed by distillation to isolate 4-methyl-2-pentanone.

of the above three methods are relatively traditional manufacturing methods, there are some disadvantages, such as the need to use a large amount of acid catalyst and produce a large amount of waste acid. Therefore, in recent years, some new manufacturing methods are also being researched and developed.

method four: biological method

biological method is a relatively new type of 4-methyl -2-pentanone manufacturing method, through the way of microbial fermentation to produce. The specific steps are as follows:

1. adding glucose, isopropanol and other raw materials into the fermenter.
2. Conversion of glucose to pyruvate by the action of microorganisms.
3.4-methyl -2-pentanone is generated by the condensation reaction of pyruvic acid and isopropanol under the action of enzyme.

biological method has the advantages of environmental protection and energy saving, it is still in the research stage and has not yet realized large-scale industrial production.

In general, there are many manufacturing methods of 4-methyl-2-pentanone, and the advantages and disadvantages of each method are different, which can be selected according to actual production needs.

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